About Reye’s syndrome
We provide evidence-based information about this rare disease - including the causes, signs and symptoms and what happens after diagnosis. We also have management advice for health professionals.
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Introduction to Reye’s syndrome
Reye’s syndrome can appear soon after a viral infection, especially a flu-like illness or chickenpox. It's is a very rare disorder which affects children and young people. Unless diagnosed and treated successfully, death or severe disability may result.
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Causes
The cause of Reye's syndrome is unknown. Some studies suggest a link with the use of the medicine, aspirin. Aspirin should only be given to children under 16 on the advice of a doctor. We explain more as well as how common it is.
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Signs and symptoms
The symptoms of Reye's syndrome usually begin a few days after a viral infection. We detail the early signs and symptoms of Reye's syndrome and offer advice to parents about how to respond to these symptoms, or fever in a child.
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After diagnosis
The NHS advise that if Reye's syndrome is diagnosed, your child will need to be immediately admitted to an intensive care unit. We explain more about treatment and survival.
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Management – advice for health profesionals
A child's life may depend on obtaining emergency treatment in the nearest children's unit. This page provides advice for paediatricians, physicians and A&E doctors.
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Reye-like syndromes
Many rare genetic (inherited) disorders of the body chemistry - called metabolic disorders - are known to cause a disorder similar to Reye's syndrome. We provide information on what is known about these syndromes and why they are important. We also give a note on screening in newborn babies.
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Metabolic disorders
The 26 identified inherited metabolic disorders which can simulate Reye's syndrome are provided by a number of organisations specialising in rare diseases. We list them under four sub-heads here.
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Life after Reye’s syndrome
We offer advice to parents of children who have survived Reye's syndrome or a Reye-like disorder - to help understand the potential needs of the child and their family, and to provide guidance in securing any necessary services.
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